For the final project, you will use the gene you identified in the gene annotation project and the protein used in protein annotation project to:
Select one disease either at the gene or protein level and provide more detailed discussion on:
General requirements:
Content | Excellent | Very Good | Good | Fair | Poor |
Points | 4 | 3 | 2 | 1 | 0 |
General Requirements | All the general requirements are met | Most of the general requirements are met | Some of the general requirements are met | A few general requirements are met | no answer |
Abstract | Very well written abstract indicating what the paper is about | Good abstract | Fairly-written abstract | Very vague abstract not indicating what the paper is about | no answer |
Disease identification | Identifies diseases and the genomic features at both gene and protein levels | Identifies at the diseases and implicated genomic features only at either protein or gene level | Identifies diseases at both protein and gene level but not the genomic features | Identifies the diseases only at either gene or protein levels and no genomic features | no answer |
Disease mechanism | Very well written description of the disease mechanism | Good description of the disease mechanism | Fair description of the disease mechanism | Vague description of the disease mechanism | no answer |
Bioinformatics approaches | Clearly describes the bioinformatics approaches | Good description of the bioinformatics approaches | Fair description of the bioinformatics approaches | Vague description of the bioinformatics approaches | No answer |
Bioinformatics and data analysis tools | Correct and good discussion identification of bioinformatics & data analysis tool | Correct tools are identified and fairly -discussed | Correct tools are identified but no discussion | Identified tools cannot be used for identifying implicated genomic features in the selected disease | No answer |
Drug targets & pathways | Identifies the correct drug targets and the implicated pathways | Identifies the drug targets but not the pathways | Identifies the pathway but no drugs | Wrong identifications of pathways and drug targets | No answer |